About Niclosamide Anthelmintic, a chlorinated salicylanilide, Anticestodal(taeniacide). Mechanism of Action of Niclosamide It excerts its vermicidal action against cestodes by inhibiting anaerobic phosphorylation of ADP by mitochondria of parasite which leads to energy depletion. The injured worms are partially digested in the intestine. Indications for Niclosamide 1.Taenia saginata 2.Diphyllobothrium latum 3.Hymenolepis nana 4.Taenia solium